Unconjugated Galanthus Nivalis Lectin (GNL)

L-1240
SKU Unit Size Price Qty
L-1240-5 5 mg
$149.00

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Description

Galanthus nivalis lectin, unlike most mannose-specific lectins, is not a metalloprotein and does not require Ca++ or Mn++ for binding. Binding seems to be preferentially directed toward structures containing (α-1,3) mannose residues. 

Specifications

More Information
Unit Size 5 mg
Applications Immunohistochemistry / Immunocytochemistry, Immunofluorescence, Blotting Applications, Glycobiology
Recommended Usage Although many buffers can be employed for reconstituting and diluting this lectin, 10 mM HEPES buffered saline, pH 8.5, 0.1 mM CaCl2 is recommended. Lectin may be preserved with 0.04% sodium azide.
Recommended Storage 2-8 °C
Conjugate Unconjugated
Sugar Specificity Mannose

Documents

Technical Information

In contrast to most mannose-binding lectins, GNL will not bind α-linked glucose. Reports indicate that this lectin binds rat and mouse IgM but not IgG. The only protein from human serum reported to bind to this lectin is α2-macroglobulin. GNL binds to many viral glycoproteins.

Inhibiting/Eluting Sugar: 100 mM - 200 mM α-methylmannoside