Ricin A Chain

L-1190
SKU Unit Size Price Qty
L-1190-1 1 mg
$193.00

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Description

Ricin A chain has been isolated from extremely toxic, highly purified RCA II. Our ricin A chain has less than 0.01% of the toxicity of the native lectin in a cell culture test system, yet is as potent as native ricin in a cell-free protein synthesis assay. The A chain is supplied in buffered saline with sodium azide as a preservative.

Please note: Ricin A chain is shipped on wet ice and requires an additional shipping charge, sold in USA only.

Specifications

More Information
Unit Size 1 mg
Applications Blotting Applications, Glycobiology
Recommended Usage CAS Number: 96638-28-7 NOTE: Ricin A Chain may precipitate irreversibly at temperatures above 30 ºC PLEASE NOTE: Although this product lacks the toxicity of native ricin, exercise caution when using Ricin A Chain.Conjugates can be extremely toxic!DO NOT LYOPHILIZE THIS PRODUCT. To ensure that the sulfhydryl group on the Ricin A Chain is available, prior to coupling add fresh reducing agent to the Ricin A Chain, followed by dialysis or gel filtration at pH 6.5.
Recommended Storage 2-8 °C, DO NOT FREEZE
Solution 10 mM sodium phosphate, 0.15 M NaCl, pH 7.5, 0.08% sodium azide, 50 mM 2-mercaptoethanol, 0.1% polyethylene glycol (M.W. 3300)
Concentration 1 mg/ml
Conjugate Unconjugated

Documents

Technical Information

Ricin A chain has been isolated from extremely toxic RCA II. Our ricin A chain has less than 0.01% of the toxicity of the native lectin in a cell culture test system, yet is as potent as native ricin in a cell-free protein synthesis assay. The A chain can be linked to other proteins such as antibodies. These antibody-toxin hybrid molecules can be used to kill specific cells with the appropriate antigenic determinant exposed, such as tumor markers on surfaces of malignant cells. The A chain is supplied in buffered saline with sodium azide as a preservative.

Please note: Ricin A chain is shipped on wet ice and requires an additional shipping charge, sold in USA only.