WS Biotin DBCO ≥99% (CCT-A116)


Click Chemistry Tools offers the highest purity WS Biotin DBCO reagent available. It is manufactured to ensure the highest possible overall product integrity, consistency and performance for the intended research applications.

A water-soluble, azide-reactive biotinylation reagent, WS DBCO-Bitoin reacts with azides via a copper-free “click chemistry” reaction to form a stable triazole without the need for copper catalyst or elevated temperatures. Often a reagent of choice in live cell surface glycans and lipids studies where the presence of cytotoxic copper catalyst is not acceptable. In application where the presence of copper is a concern WS DBCO Bitoin is an ideal alternative to copper requiring biotin-alkynes.


Unit Size1mg, 5mg, 25mg, 100mg
Molecular weight653.77
Chemical compositionC31H35N5O7S2
SolubilityWater, DMSO, DMF
Purity>99% (HPLC)
AppearanceWhite to grey amorphous solid
Storage Conditions-20°C. Desiccate
Shipping ConditionsAmbient temperature

Selected References

  1. Simon P. Wisnovsky, et al. (2020). Metabolic precision labeling enables selective probing of O-linked N-acetylgalactosamine glycosylation. PNAS, 117 (41), 25293-25301. [PNAS]
  2. Suttapitugsakul, S., et al. (2019). Surface Glycoproteomic Analysis Reveals That Both Unique and Differential Expression of Surface Glycoproteins Determine the Cell Type. Anal. Chem., 91(10), 6934–42. [PubMed]

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