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TCO-PEG4-Acid (CCT-1088)

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Description

An amine-reactive, non-activated building block with enhanced solubility in aqueous media used for derivatizing amine-containing molecule in the presence of activators (e.g. EDC, or HATU) through a stable amide bond.

Specifications

Unit Size25 mg, 100 mg, 500 mg
Molecular weight417.49
Chemical compositionC20H35NO8
CASN/A
SolubilityDMSO, DMF, DCM, THF, Chloroform
Purity>95% (HPLC)
AppearanceColorless to slightly yellow oil
Storage Conditions-20°C. Desiccate
Shipping ConditionsAmbient temperature

Selected References

  1. Marquard, A.N., et al. (2020). Expanding the Scope of Antibody Rebridging with New Pyridazinedione-TCO Constructs. Bioconjug Chem.31(6), 1616-23. [PubMed]

Applicable patents and legal notices are available at legal notices.

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