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PC Biotin-NHS ester (CCT-1225)



PC Biotin-NHS Ester as a unique amine reactive, photocleavable biotin reagent that allows for reagent-free release of the captured biomolecules from streptavidin beads. This reagent contains a biotin moiety linked to the amine reactive N-hydroxysuccinimidyl (NHS) mixed carbonate through a spacer arm containing a photocleavable moiety. The NHS portion of this compound reacts specifically with primary amine groups on the target molecule(s) to form a carbamate linkage. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2).


Unit Size4 x 1 mg, 10 mg, 25 mg, 100 mg
Molecular weight840.89
Chemical compositionC36H52N6O15S
SolubilityDMSO, DMF, DCM, THF, Chloroform
AppearanceSlightly yellow amorphos solid to oil
Storage Conditions-20°C. Desiccate
Shipping ConditionsAmbient temperature

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