Products Results    (6)

Concanavalin A (Con A)

Con A recognizes α-linked mannose present as part of a “core oligosaccharide” in many serum and membrane glycoproteins. At neutral and alkaline pH, Con A exists as a tetramer of four identical subunits; below pH 5.6, Con A dissociates into active dimers of 52 kDa. Acetylation, succinylation, or other derivatizations can also produce stable forms with dimeric structures. (See succinylated Con A). “Nicks” in the sequence are often present in the purest preparations due to hydrolytic damage within the seeds.

Con A requires calcium or manganese ions at each of its four saccharide binding sites. Although these divalent metal ions are bound tightly to the polypeptide structure, buffers which can bind calcium (such as phosphate) generally should be avoided in diluting Con A, since a gradual loss in activity may occur.

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  1. Biotinylated Concanavalin A (Con A)
    Biotinylated Concanavalin A (Con A)
    Cat. No: B-1005
    Unit Size: 5 mg
  2. Cy3 labeled Concanavalin A (Con A)
    Cy3 labeled Concanavalin A (Con A)
    Cat. No: CL-1003
    Unit Size: 1 mg
  3. Rhodamine labeled Concanavalin A (Con A)
    Rhodamine labeled Concanavalin A (Con A)
    Cat. No: RL-1002
    Unit Size: 25 mg
  4. Fluorescein Labeled Concanavalin A (Con A)
    Fluorescein Labeled Concanavalin A (Con A)
    Cat. No: FL-1001
    Unit Size: 25 mg
  5. Agarose bound Concanavalin A (Con A)
    Agarose bound Concanavalin A (Con A)
    Cat. No: AL-1003
    Unit Size: 10 ml, 100 ml
  6. Unconjugated Concanavalin A (Con A)
    Unconjugated Concanavalin A (Con A)
    Cat. No: L-1000
    Unit Size: 500 mg
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