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Enzyme Substrate Properties

Along with the traditional chromogenic substrates, Vector Laboratories offers a wide variety of proprietary enzyme substrates.  These proprietary substrates provide novel color choices essential for staining antigens in pigmented tissues and melanomas as well as for localizing multiple antigens in the same tissue section.  Several can be effectively viewed under darkfield or electron microscopy.  Many of our substrates have unique spectral profiles that may be useful in colocalization of antigens using spectral imaging systems.  Still others are heat resistant - important for IHC/ISH double labeling applications and multiplexing IHC where heat induced epitope retrieval (HIER) is performed after substrate development to prevent artifactual costaining.

Enzyme Substrate Properties