Incorporating glycan analysis into your workflows is easier than you may think–especially when you use lectins, which are compatible with many commonly used lab assays. Join us as we walk through the key considerations to help you get started.
How can we do even more to help researchers? That’s a question we ask a lot here at Vector Laboratories, and this June it led us to launch a blog. Since then, it’s been our honor to bring you stories about innovative scientists and share insights to help you advance your research. Here are a few of our most popular posts from 2021, and we’re looking forward to many more tips and stories in 2022!
Lectins are essential in recognizing abnormal cell glycome and mediating tumor progression. That said, they can also be leveraged to enhance our knowledge of the glycome profiles of various cancers.
Why does glycobiology—the study of sugar chains—matter so much to our health? From the simplest to the most branched, carbohydrates are the key players in cellular functions—both healthy and pathological. This article summarizes the key elements of glycobiology in a nutshell.
Glycosylation networks have massive biomarker potential for breast cancer diagnosis and treatment. This study explores yet another alteration in breast cancer glycan profile: bisecting GlcNAc.
The study closely examined the glycan structures and glycoprotein expression in muscle-invasive bladder cancer, leading to the discovery of a novel biomarker: HOMER3. This article elaborates on preliminary results about the role of HOMER3 in bladder cancer metastasis.
This study explores how the sickle cell trait could help millions of people in Sub-Saharan Africa, a high-risk malaria zone, develop resistance against malaria.
Hypersialylation of glycans is one of the key drivers in cell differentiation in cancer, including pancreatic ductal adenocarcinoma (PDAC) cells. In this article, we review a study investigating how this mechanism led to the differentiation of tumor monocytes into malignant tumor macrophages associated with low survival rates in patients.
In this publication highlight, we review a study examining the impact of macrophage-derived microparticles on the tumor microenvironment and their synergistic effect on anti-PD-1 antibody activity.
