SpeakEasy Science Blog

What’s in a name? Glycans and sugars and lectins … Oh my!

Why does glycobiology—the study of sugar chains—matter so much to our health? From the simplest to the most branched, carbohydrates are the key players in cellular functions—both healthy and pathological. This article summarizes the key elements of glycobiology in a nutshell.

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The Waiting Game: A Search for a Streamlined IHC Protocol

Picture this: a chemist walks into a lab and asks his colleagues how to transition some immunohistochemistry (IHC)-stained slides in a buffer solution to coverslip with a non-aqueous mounting media. From his perspective, it’s a simple problem, and it should have a similarly simple solution. Does it? Read this blog article to find out.

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Dial up the Contrast with Counterstaining

When scientists detect targets of interest with immunohistochemistry (IHC), antibody binding and substrate detection alone often produce a perplexing picture where the target lacks context. Luckily there’s a solution. Counterstaining IHC samples after enzymatic detection spatially orients the target within its surroundings, which can help guide researchers as they analyze their results.

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