Articles by Sierra Cotton

Articles by Sierra Cotton

My staining didn’t work, part 2: Absence of positive staining in IHC and IF

One pain for IHC and IF staining can be the lack of positive staining on your tissue sections. In this blog post, we will offer tips and tricks for overcoming the absence of positive staining in IHC and IF. 

October 12, 2022

How to protect your tissue from photobleaching

This blog post will walk you through strategies in four different categories to protect your immunofluorescent tissue section from photobleaching.

September 14, 2022

A behind-the-scenes look at the development of Glysite Scout

Glysite Scout Glycan Screening Kits, Immunofluorescence is the newest product from Vector Laboratories. We sat down with Senior Scientist August Estabrook to learn more about the development of this brand-new product.

August 3, 2022

How to use Glysite Scout Glycan Screening Kits

This how-to blog post will show you how to use the GlysiteTM Scout Glycan Screening Kit—regardless of which fluorophore your kit comes with. The post will walk you through everything from how to prepare and stain your slides through mounting your finished result

July 27, 2022

A time for celebration at Vector Laboratories

For the first time in 2022, all employees—remote and in-office—gathered at the new home for Vector Laboratories to celebrate our relocation and our accomplishments so far in 2022.

June 29, 2022

Company veteran: A day in the life of a research director at Vector Laboratories

Erika Leonard, Director of R&D, has been with Vector Laboratories for almost 30 years. We sat down to discuss her time at the company and the various roles she’s taken on.

June 15, 2022

5 sources of non-specific staining and background in IHC and IF

Identifying sources of non-specific staining is crucial for determining potential solutions to improve your staining results. This blog post will briefly walk you through commonly encountered sources of non-specific staining in IHC and IF applications.

June 8, 2022

How to prevent tissue and reagent loss on your slides

You spend a lot of time collecting and preparing your tissue samples. Learn tips and tricks to ensure those samples are evenly stained and retained on your slides.

May 4, 2022

Connecting the dots: a day in the life of a senior scientist at Vector Laboratories

August Estabrook, a senior scientist at Vector Laboratories, came to love science starting in high school and at one point dreamed of opening a microbrewery. Now, August spends his days connecting the dots to develop leading proteomic and glycomic products.

April 13, 2022

How to improve your immunofluorescence by overcoming autofluorescence

Interfering background signal, such as autofluorescence, which is fluorescence inherent or endogenous to tissue, cell, or due to certain fixatives, can hamper your ability to accurately distinguish real target antigen expression. In a recent webinar, Dr. Craig Pow discussed common causes of target signal interference, controls to help distinguish background noise from true signal, ways to reduce or eliminate autofluorescence, case studies of autofluorescence quenching, and tips to preserve immunofluorescent signal, such as through the use of Vector® TrueVIEW® Autoflurorescence Quenching Kit. You can watch the full on-demand webinar or keep reading for tips and tricks from the Q&A session.

March 2, 2022